The intersection of blockchain technology and scientific research is giving rise to a transformative movement known as decentralized science (DeSci). This emerging field is reshaping how research is conducted, funded, and shared by leveraging blockchain’s inherent transparency and accessibility. In 2024, the healthcare sector experienced significant venture capital investment flowing into DeSci initiatives, which aim to revolutionize clinical trials, health data management, and personal health and wellness.

In this article, we explore some of the most interesting and innovative projects in DeSci, focusing on those that go beyond just DAOs and funding initiatives. From blockchain-powered biobanks to DNA-based digital twins designed to enhance personal wellness strategies, these projects reimagine scientific collaboration and create new opportunities for personalized healthcare and genetic research.

Holiverse: Pioneering the Holistic Wellness Metaverse

Holiverse represents an ambitious vision within the broader DeSci ecosystem, developing a wellness optimization platform that combines DNA analysis, Digital Twin technology, and metaverse capabilities. The Holiverse Health department, led by Dr. Dmitry Chebanov, who has a background in bioinformatics and drug discovery, has garnered significant attention from early investors.

The platform is currently undergoing a fundamental rebuild due to severe technical challenges. However, even during this reconstruction phase, they have attracted new talent and fostered a more comprehensive vision for its future.

The Holiverse’s distinctive feature is its approach to creating interconnected network effects that benefit all participants:

• Scientific research drives personalized wellness recommendations.
• User data enhances predictive health models.
• Healthcare providers gain access to comprehensive patient insights.
• Users receive financial incentives for sharing anonymized health data.
• Community participation shapes further platform development.

By integrating these elements into a metaverse environment, Holiverse aims to create practical tools for enhancing users’ real-world wellness.

While the platform’s success will depend on its successful reconstruction and ability to execute its vision, its holistic approach to health optimization represents an intriguing development in the emerging DeSci landscape—an opportunity not to be overlooked.

Genomics and DNA: Genomes.io

Genomes.io is a project that offers DNA testing and rewards users for contributing genomic data to scientific research. It focuses on the role of genetics in human longevity and the potential of gene therapy to extend lifespan.

The platform allows users to upload existing genomic data from services like 23andMe, MyHeritage, or Ancestry.com or obtain whole genome sequencing through Genomes.io’s services. Participants retain full ownership and control over their data, with the option to earn $GENOME tokens by contributing to scientific research.

(Source: Genomes.io)

The platform provides detailed insights into genetic predispositions for various health conditions, including Parkinson’s Disease, Ulcerative Colitis, and others, using GWAS methodology.

Recently, Genomes.io has partnered with Bittensor to develop AI-driven models for predicting drug responses based on synthetic genetic profiles.

With the ambitious Billion Genomes Project, the platform seeks to secure 1 billion genomes over five years beginning in 2025, with users earning points convertible to $GENOME tokens.

(Source: Google Play)

Winner of the 2023 Deloitte Tech Fast 50 Challenge Award, Genomes.io provides these services via a dedicated mobile app, merging accessibility with robust security standards.

Health Data Management: AminoChain

AminoChain is developing a decentralized biobank that transforms how medical institutions and biopharmaceutical companies share and trade biosamples.

(Source: aminochain.io)

The platform’s cornerstone is the Specimen Center—a peer-to-peer marketplace where stem cell donors can tokenize their samples and receive compensation when their cells are purchased for research.

In Q3, 2024, AminoChain secured a $5 million seed round led by the venture capital firm Andreessen Horowitz (a16z)—their first investment in a DeSci project.

However, AminoChain’s growth has been hampered by headwinds, as the platform is currently involved in a legal dispute with GenoBank over BioNFT patent rights, which has divided the DeSci community.

About GenoBank:

GenoBank focuses on secure DNA data storage and genetic testing, particularly on bio-digital decolonization for underserved communities. The platform enables users to control their genetic information while ensuring compliance with privacy standards.

Health Data Wearables: Pulse

Pulse combines a health-tracking wearable with blockchain technology, allowing users to monitor vital metrics, receive AI-powered insights, and monetize their health data.

(Source: pulse.site)

The project aims to create a secure digital twin—a comprehensive virtual health profile that integrates data from various sources, including wearables and outside electronic health records.

Both investors and early adopters have shown keen interest in the project:

• The first two pre-order batches sold out within 48 hours.
• In Q3 2024, the project secured $1.8 million in pre-seed funding from notable investors, including Solana co-founder Anatoly Yakovenko.
• In December 2024, Pulse launched the first on-chain wearable study to assess supplement efficacy.

(@PulseNoLimits on X)

With devices set to ship in Q1 2025, Pulse is positioned as a key player in the decentralized science (DeSci) sector, contributing to Solana’s growing influence in this emerging field.

Longevity and Health: Rejuve.AI

Rejuve.AI combines machine learning and blockchain technology to advance longevity research through data-driven insights. The platform analyzes aggregated health data to provide personalized health insights, operating on a token-based system that incentivizes data sharing and collaboration among researchers, healthcare providers, and individuals.

(Source: rejuve.ai)

Recent updates include progress on the Biological Age Estimator alongside new crypto wallet integration capabilities.

The platform’s reach expanded in December 2024 through a strategic partnership with ImagineHealth Thailand, allowing payments in $RJV tokens for healthcare services starting in 2025.

To Sum It Up

The projects we’ve explored show how blockchain is breaking down barriers between patients, researchers, and healthcare providers. DeSci initiatives are transforming health data into secure, tradable assets, enabling personalized medicine and accelerating scientific breakthroughs. It’s exciting to witness this ecosystem take shape, bringing us closer to healthcare that is not only more effective but also more accessible and transparent for everyone involved.

1st push

DeSci in Action: Projects Reshaping Healthcare in 2025

The intersection of blockchain technology and scientific research is giving rise to a transformative movement known as decentralized science (DeSci). This emerging field is reshaping how research is conducted, funded, and shared by leveraging blockchain’s inherent transparency and accessibility. In 2024, the healthcare sector experienced significant venture capital investment flowing into DeSci initiatives, which aim to revolutionize clinical trials, health data management, and personal health and wellness.

In this article, we explore some of the most interesting and innovative projects in DeSci, focusing on those that go beyond just DAOs and funding initiatives. From blockchain-powered biobanks to DNA-based digital twins designed to enhance personal wellness strategies, these projects reimagine scientific collaboration and create new opportunities for personalized healthcare and genetic research.

Health Data Management: AminoChain

AminoChain is developing a decentralized biobank that transforms how medical institutions and biopharmaceutical companies share and trade biosamples.

(Source: aminochain.io)

The platform’s cornerstone is the Specimen Center—a peer-to-peer marketplace where stem cell donors can tokenize their samples and receive compensation when their cells are purchased for research.

In Q3, 2024, AminoChain secured a $5 million seed round led by the venture capital firm Andreessen Horowitz (a16z)—their first investment in a DeSci project.

However, AminoChain’s growth has been hampered by headwinds, as the platform is currently involved in a legal dispute with GenoBank over BioNFT patent rights, which has divided the DeSci community.

About GenoBank:

GenoBank focuses on secure DNA data storage and genetic testing, particularly on bio-digital decolonization for underserved communities. The platform enables users to control their genetic information while ensuring compliance with privacy standards.

Longevity and Health: Rejuve.AI

Rejuve.AI combines machine learning and blockchain technology to advance longevity research through data-driven insights. The platform analyzes aggregated health data to provide personalized health insights, operating on a token-based system that incentivizes data sharing and collaboration among researchers, healthcare providers, and individuals.

(Source: rejuve.ai)

Recent updates include progress on the Biological Age Estimator alongside new crypto wallet integration capabilities.

The platform’s reach expanded in December 2024 through a strategic partnership with ImagineHealth Thailand, allowing payments in $RJV tokens for healthcare services starting in 2025.

Genomics and DNA: Genomes.io

Genomes.io is a project that offers DNA testing and rewards users for contributing genomic data to scientific research. It focuses on the role of genetics in human longevity and the potential of gene therapy to extend lifespan.

The platform allows users to upload existing genomic data from services like 23andMe, MyHeritage, or Ancestry.com or obtain whole genome sequencing through Genomes.io’s services. Participants retain full ownership and control over their data, with the option to earn $GENOME tokens by contributing to scientific research.

(Source: Genomes.io)

The platform provides detailed insights into genetic predispositions for various health conditions, including Parkinson’s Disease, Ulcerative Colitis, and others, using GWAS methodology.

Recently, Genomes.io has partnered with Bittensor to develop AI-driven models for predicting drug responses based on synthetic genetic profiles.

With the ambitious Billion Genomes Project, the platform seeks to secure 1 billion genomes over five years beginning in 2025, with users earning points convertible to $GENOME tokens.

(Source: Google Play)

Winner of the 2023 Deloitte Tech Fast 50 Challenge Award, Genomes.io provides these services via a dedicated mobile app, merging accessibility with robust security standards.

Health Data Wearables: Pulse

Pulse combines a health-tracking wearable with blockchain technology, allowing users to monitor vital metrics, receive AI-powered insights, and monetize their health data.

(Source: pulse.site)

The project aims to create a secure digital twin—a comprehensive virtual health profile that integrates data from various sources, including wearables and outside electronic health records.

Both investors and early adopters have shown keen interest in the project:

• The first two pre-order batches sold out within 48 hours.
• In Q3 2024, the project secured $1.8 million in pre-seed funding from notable investors, including Solana co-founder Anatoly Yakovenko.
• In December 2024, Pulse launched the first on-chain wearable study to assess supplement efficacy.

(@PulseNoLimits on X)

With devices set to ship in Q1 2025, Pulse is positioned as a key player in the decentralized science (DeSci) sector, contributing to Solana’s growing influence in this emerging field.

Holiverse: Pioneering the Holistic Wellness Metaverse

Holiverse represents an ambitious vision within the broader DeSci ecosystem, developing a wellness optimization platform that combines DNA analysis, Digital Twin technology, and metaverse capabilities. The Holiverse Health department, led by Dr. Dmitry Chebanov, who has a background in bioinformatics and drug discovery, has garnered significant attention from early investors.

The platform is currently undergoing a fundamental rebuild due to severe technical challenges. However, even during this reconstruction phase, they have attracted new talent and fostered a more comprehensive vision for its future.

The Holiverse’s distinctive feature is its approach to creating interconnected network effects that benefit all participants:

• Scientific research drives personalized wellness recommendations.
• User data enhances predictive health models.
• Healthcare providers gain access to comprehensive patient insights.
• Users receive financial incentives for sharing anonymized health data.
• Community participation shapes further platform development.

By integrating these elements into a metaverse environment, Holiverse aims to create practical tools for enhancing users’ real-world wellness.

While the platform’s success will depend on its successful reconstruction and ability to execute its vision, its holistic approach to health optimization represents an intriguing development in the emerging DeSci landscape—an opportunity not to be overlooked.